Obesity and diabetes mellitus and left ventricular hypertrophy in patients with arterial hypertension

Agnieszka Sędkowska, Magdalena Gawron-Kiszka, Maciej Tomaszewski, Jacek Kowalczyk, Witold Streb, Ewa Markowicz-Pawlus, Jadwiga Obrębska, Zbigniew Kalarus, Ewa Żukowska-Szczechowska

Abstract

Background The aim of this study was to assess the influence
of obesity and diabetes mellitus on left ventricular
hypertrophy in patients with arterial hypertension.

Material and methods Study population consisted of 554
patients with hypertension (62% men, 38% women), and
97 patients with hypertension and concomitant diabetes
mellitus (DM) (61% men, 39% women). The mean age in
these two groups was 53 ± 13 years v. 58 ± 8 years respectively.
We performed echocardiography as well as blood
pressure (twice) and waist and hip circumference measurements.
Body mass index (BMI) was assessed.

Results Left ventricular mass (LVM) and left ventricular
mass index (LVMI) were significantly higher in the group
with hypertension and concomitant DM than in the
group without DM, LVM — 280.6 ± 67.4 g v. 247.3 ±
74.8 g, p < 0.0001, LVMI — 145.2 ± 33 g/m2 v. 129.9 ±
36 g/m2, p < 0.0001. In patients with hypertension without
DM, BMI positively correlated with LVMI (r = 0.17,
p < 0,0001) in men and in women. Waist/hip ratio positively
correlated with LVMI in women (r = 0.26, p <
0.0001). In the group of patients with concomitant DM,
BMI and waist/hip ratio didn’t correlate with left ventricular
hypertrophy.

Conclusions Higher body mass index and abdominal
obesity in women are risk factors for left ventricular hypertrophy.
Left ventricular hypertrophy is more prevalent in
the group with concomitant DM.

Arterial Hypertension 2011, vol. 15, no 2, pages 93–101.

Keywords

arterial hypertension; diabetes mellitus; left ventricular hypertrophy

Refbacks

  • There are currently no refbacks.

By  "Via Medica sp. z o.o." sp.k., ul. Świętokrzyska 73, 80–180 Gdańsk

tel.:+48 58 320 94 94, faks:+48 58 320 94 60, e-mail:  viamedica@viamedica.pl