Vol 42, No 4 (2004)
Original paper
Submitted: 2011-12-19
Published online: 2005-02-12
Expression of Fas receptor on peripheral blood lymphocytes from patients with non-small cell lung cancer.
Grazyna Hoser, Danuta Wasilewska, Joanna Domagała-Kulawik
Folia Histochem Cytobiol 2004;42(4):249-252.
Vol 42, No 4 (2004)
ORIGINAL PAPERS
Submitted: 2011-12-19
Published online: 2005-02-12
Abstract
In recent years many data indicate that lymphocytes from cancer patients undergo increased apoptosis. The objective of this study was to evaluate the expression of Fas receptor on lymphocytes obtained from patients with lung cancer. Eighteen patients with non-small cell lung cancer and 18 healthy volunteers were investigated. Expression of Fas (CD95) on CD4+ and CD8+ blood lymphocytes was evaluated by flow cytometry. The proportion of blood Fas+ lymphocytes was significantly higher in lung cancer patients when compared with healthy individuals and in smokers when compared with nonsmokers.
Abstract
In recent years many data indicate that lymphocytes from cancer patients undergo increased apoptosis. The objective of this study was to evaluate the expression of Fas receptor on lymphocytes obtained from patients with lung cancer. Eighteen patients with non-small cell lung cancer and 18 healthy volunteers were investigated. Expression of Fas (CD95) on CD4+ and CD8+ blood lymphocytes was evaluated by flow cytometry. The proportion of blood Fas+ lymphocytes was significantly higher in lung cancer patients when compared with healthy individuals and in smokers when compared with nonsmokers.
Title
Expression of Fas receptor on peripheral blood lymphocytes from patients with non-small cell lung cancer.
Journal
Folia Histochemica et Cytobiologica
Issue
Vol 42, No 4 (2004)
Article type
Original paper
Pages
249-252
Published online
2005-02-12
Page views
1294
Article views/downloads
1004
Bibliographic record
Folia Histochem Cytobiol 2004;42(4):249-252.
Authors
Grazyna Hoser
Danuta Wasilewska
Joanna Domagała-Kulawik