Vol 46, No 2 (2008)
Original paper
Submitted: 2011-12-19
Published online: 2008-06-04
Thiocyanate concentration in saliva of cystic fibrosis patients.
Łukasz Minarowski, Dorota Sands, Alina Minarowska, Alicja Karwowska, Anetta Sulewska, Marek Gacko, Elzbieta Chyczewska
DOI: 10.2478/v10042-008-0037-0
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Folia Histochem Cytobiol 2008;46(2):245-246.
Vol 46, No 2 (2008)
ORIGINAL PAPERS
Submitted: 2011-12-19
Published online: 2008-06-04
Abstract
Thiocyanates (SCN-) are ubiquitous in nature. There are indispensable part of host defense system that act as a substrate for lactoperoxidase (LPO). In our study we present initial data on SCN- concentration in saliva of CF patients in comparison to healthy non-smokers and healthy smokers. 5 ml of saliva was collected from each subject to a sterile tube and thiocyanate concentration was measured in each sample. The results of the measurements are presented on Fig. 1. Mean concentration of SCN- in saliva of CF patients was 0.031 +/- 0.0052 g/l, in healthy non-smokers 0.039 +/- 0.0048 g/l and in healthy smokers 0.048 +/- 0.0161 g/l. The differences between each group were statistically significant. Studies on larger group of patients and probably on different material (BALF or induced sputum) should present interesting data complementing the in vitro studies.
Abstract
Thiocyanates (SCN-) are ubiquitous in nature. There are indispensable part of host defense system that act as a substrate for lactoperoxidase (LPO). In our study we present initial data on SCN- concentration in saliva of CF patients in comparison to healthy non-smokers and healthy smokers. 5 ml of saliva was collected from each subject to a sterile tube and thiocyanate concentration was measured in each sample. The results of the measurements are presented on Fig. 1. Mean concentration of SCN- in saliva of CF patients was 0.031 +/- 0.0052 g/l, in healthy non-smokers 0.039 +/- 0.0048 g/l and in healthy smokers 0.048 +/- 0.0161 g/l. The differences between each group were statistically significant. Studies on larger group of patients and probably on different material (BALF or induced sputum) should present interesting data complementing the in vitro studies.
Title
Thiocyanate concentration in saliva of cystic fibrosis patients.
Journal
Folia Histochemica et Cytobiologica
Issue
Vol 46, No 2 (2008)
Article type
Original paper
Pages
245-246
Published online
2008-06-04
Page views
5455
Article views/downloads
2609
DOI
10.2478/v10042-008-0037-0
Bibliographic record
Folia Histochem Cytobiol 2008;46(2):245-246.
Authors
Łukasz Minarowski
Dorota Sands
Alina Minarowska
Alicja Karwowska
Anetta Sulewska
Marek Gacko
Elzbieta Chyczewska