Vol 9, No 3-4 (2008): Practical Diabetology
Review article
Published online: 2008-07-04
Opinions on the role of chromium (III) in the prevention and control of diabetes
Diabetologia Praktyczna 2008;9(3-4):168-175.
Abstract
In this work the review of the literature about the
role of chromium (III) in prevention and control of
diabetes was presented. Studies indicate that Cr (III)
is necessary for regulatation of carbohydrate and lipid
metabolism mainly due to increasing the number
of insulin receptors and its activation by phosphorylation.
Some authors believe that chromium (III) deficiency
can lead to glucose intolerance and symptoms
of type 2 diabetes. Moreover, in type 2 diabetic
patients tissular chromium levels may be decreased,
therefore some authors recommend chromium supplementation.
The animal and human studies in that
subject as well as factors affecting chromium supplementation
were discussed. However, due to methodological
limitations of many clinical studies, the
statements of major diabetes associations concerning
recommendation from chromium supplementation
in individuals with diabetes and obesity still
remains negative.
Keywords: diabeteschromiumsupplementation